Cell expansion is the process of growing cells in vitro for various applications such as research, drug discovery, cell therapy, tissue engineering and bioproduction. Cell expansion involves the use of cell culture media, reagents, instruments and consumables to maintain optimal conditions for cell growth and differentiation. The global cell expansion market was valued at USD 21 billion in 2023 and is expected to reach USD 81 billion by 2032, growing at a compound annual growth rate (CAGR) of 16.20% during the forecast period.
The global cell expansion market is set to continue its growth trajectory from 2017 to 2032, driven by the rising demand for cell-based therapies, technological advancements, and increased investment in research and development. Despite facing challenges such as high costs and regulatory hurdles, the market is poised for significant expansion, offering substantial opportunities for companies engaged in the development and provision of cell expansion products and technologies.
Key Drivers and Constraints
The major factors driving the growth of the cell expansion market are the increasing prevalence of chronic diseases, such as cancer, diabetes, cardiovascular diseases and autoimmune disorders, that require cell-based therapies and personalized medicine. The rising demand for stem cell research and regenerative medicine, the growing adoption of biopharmaceuticals and biosimilars, and the technological advancements in cell culture equipment and techniques are also contributing to the market growth. Moreover, the emergence of novel applications of cell expansion, such as organoids, organ-on-a-chip and 3D bioprinting, are creating new opportunities for the market players.
However, the cell expansion market faces some challenges, such as the high cost and complexity of cell culture procedures, the ethical and regulatory issues related to the use of animal and human cells, the risk of contamination and infection, and the lack of skilled professionals and standardization in the field. These factors may hamper the market growth and limit its potential.
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Key Trends and Developments
The cell expansion market is witnessing some key trends and developments, such as the increasing adoption of automation and artificial intelligence (AI) in cell culture processes, the development of novel cell culture media and reagents, the integration of microfluidics and nanotechnology in cell expansion devices, and the expansion of cell banking and biobanking services. These trends and developments are expected to enhance the efficiency, quality, scalability and reproducibility of cell expansion and offer new possibilities for the market players.
| Trend/Development | Description | Example |
| Increasing adoption of automation and AI in cell culture processes | Automation and AI are being increasingly used in cell culture processes to enhance efficiency and quality. | Robotic systems for cell culture and AI algorithms for data analysis |
| Development of novel cell culture media and reagents | New cell culture media and reagents are being developed to improve cell expansion. | Advanced cell culture media formulations and growth factors |
| Integration of microfluidics and nanotechnology in cell expansion devices | Microfluidics and nanotechnology are being integrated into cell expansion devices to improve scalability and reproducibility. | Microfluidic cell culture systems and nanoscale sensors |
| Expansion of cell banking and biobanking services | Cell banking and biobanking services are expanding to offer new possibilities for market players. | Large-scale cell storage facilities and biobanks for research |
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Market Segmentation
The cell expansion market can be segmented by product, cell type, application, end user and region.
| Market Segment | Sub-categories | Description |
| Product | – Consumables
· Media · Reagent · SERA · Disposables – Instruments · Cell Expansion Supporting Equipment · Bioreactors · Automated Cell Expansion Systems |
The product segment encompasses everything from consumables (including media, reagents, SERA, and disposables) to instruments such as cell expansion supporting equipment, bioreactors, and automated cell expansion systems. These are essential for the process of cell cultivation and expansion. |
| Cell Type | – Human Cell – Animal Cell |
The market differentiates products based on their application to human and animal cells, catering to a broad range of research and therapeutic applications. |
| Application | – Regenerative Medicine and Stem Cell Research – Cancer Research – Drug Screening and Development – Tissue Engineering – Other Applications |
Applications of cell expansion cover regenerative medicine and stem cell research, cancer research, drug screening and development, tissue engineering, and other emerging fields, highlighting the versatility of cell expansion technologies. |
| End User | – Biotechnology and Biopharmaceutical Companies – Research Institutes – Cell Banks – Other End User |
End users include biotechnology and biopharmaceutical companies, research institutes, and cell banks, among others, indicating the wide usage of cell expansion technologies across various sectors of life sciences. |
| Region | – North America – Europe – Asia Pacific – Latin America – Middle East and Africa |
The market’s geographical distribution spans North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa, reflecting the global demand and the integral role of cell expansion technologies in the biotechnology and pharmaceutical industries worldwide. |
This table provides a comprehensive overview of the global cell expansion market.
Competitive Landscape
The cell expansion market is highly competitive and fragmented, with the presence of several global and regional players. The key players in the market include Thermo Fisher Scientific, Merck KGaA, Becton, Dickinson and Company, GE Healthcare, Danaher Corporation, Lonza Group, Corning Incorporated, Miltenyi Biotec, STEMCELL Technologies, and Terumo Corporation. These players are adopting various strategies, such as product launches and enhancements, mergers and acquisitions, partnerships and collaborations, and expansions and investments, to gain a competitive edge and increase their market share. Some of the recent developments in the market are:
| Date | Company | Action |
| March 2021 | Thermo Fisher Scientific | Launched Gibco CTS Rotea Counterflow Centrifugation System |
| February 2021 | Merck KGaA | Acquired AmpTec |
| January 2021 | Becton, Dickinson and Company | Launched BD Rhapsody Whole Transcriptome Analysis (WTA) Amplification Kit |
| December 2020 | GE Healthcare | Acquired Asymptote |
| November 2020 | Danaher Corporation | Completed acquisition of Cytiva |
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